[SHAPESHIFTER] Longevity is transforming the present and the future
"CFA Institute, a global organization of investment professionals, recently published four provocative articles showing how longevity trends are affecting people’s lifestyle, lifespan, workplace, and finances."
[TIME TO CUT BACK?] Personal factors affect willingness to curb med use
"Researchers in Japan explored older adults’ perspectives on proactive deprescribing of unneeded medications, identified enablers and barriers, and developed a typology of patient attitudes to inform patient-centered deprescribing interventions. They did this by conducting interviews with 20 patients in Japan ages 65 years or older who were receiving five or more oral medications. "
[FEEL BETTER NOW!] New well-being app promotes mental health, resilience
"Researchers from NeuRA and the University of New South Wales (UNSW) Sydney have launched a new app aimed at boosting adult wellbeing and resilience. The mobile application, called ReNeuWell, shifts the focus from managing distress to actively promoting mental flourishing, offering a neuroscience-backed, personalized approach to mental health."
[DISCONNECTED?] Age-related changes in brain networks could reduce sociability
"Social interaction has been shown to prolong lifespan and healthspan. For older adults living alone, social interaction largely comes from formal social participation, and thus depends on the sociability of the individual, according to the authors of a recent study that aimed to understand the effect of age on sociability, and the possible mechanisms behind the change. "
[NO CHEERS] Low awareness of link between alcohol and cancer
"Alcohol is a leading preventable cause of cancer, but public awareness of the connection remains strikingly low in the United States, with just 40% of American adults recognizing alcohol as a cancer risk, according to a survey-based study from The University of Texas MD Anderson Cancer Center, Houston."
In healthy aging, carb quality counts
"Study links midlife intakes of high-quality carbohydrates and dietary fiber to better health in older women"
New scientific articles highlight potential link between microplastics in ultra-processed foods and brain health
"Groundbreaking collection of four articles in Brain Medicine examines alarming spoonful of microplastics in human brains, with possible links to depression and dementia"
USC study reveals link between type 2 diabetes and brain health in older adults from various populations
"New neuroimaging-based research reveals diabetes-related brain atrophy in older adults from different backgrounds"
New research study reveals sedentary behavior is an independent risk factor for Alzheimer’s disease
"Over 6 million Americans are impacted by Alzheimer’s disease, and researchers from Vanderbilt University Medical Center and the University of Pittsburgh are discovering how lifestyle habits can impact the likelihood of developing the disease. According to a new research study published in Alzheimer's & Dementia: The Journal of the Alzheimer's Association, researchers found that increased sedentary behavior, time spent sitting or lying down, in aging adults was associated with worse cognition and brain shrinkage in areas related to risk for developing Alzheimer’s disease."
Eldercare robot helps people sit and stand, and catches them if they fall
"The new design could assist the elderly as they age in place at home."
Seeing well-designed gardens could relax us almost immediately because we look at them differently
"In well-designed gardens, our gaze shifts quicker and more often. Researchers believe this could be key to understanding the relaxing effects gardens can have on viewers."
Blood thinners called factor Xa inhibitors lower heart risk in elderly with atrial fibrillation
"“To the best of our knowledge, this is the first study to address the effects of Xa-Is on composite cardiovascular events, congestive heart failure, arteriosclerotic disease, and cardiovascular death among very old patients with NVAF over a long-term follow-up period.”"
Including pork in plant-forward diets makes meals more appealing and just as healthy, study finds
"A newly published clinical feeding study out of South Dakota State University suggests that lean pork can play a central role in plant-forward dietary patterns for aging adults, offering high-quality protein, broad acceptability and alignment with current dietary guidance.i* "
Aging and DNA damage: investigating the microbiome’s stealthy impact – a perspective
"The authors detail how a balanced microbiome (eubiosis) sustains immune tolerance and systemic health, while dysbiosis disturbs gut barrier integrity and promotes inflammatory cascades. This section underscores Toll-like receptors, the gut-lung axis, and short-chain fatty acids (SCFAs) as mediators of microbiome–immune dialogue. Case studies link microbiota composition to diseases ranging from COVID-19 and chronic lung conditions to autoimmune disorders, mental health, and even zoonotic infections like leptospirosis. These findings emphasize the microbiome's systemic reach beyond the gut."
Bitter taste receptors in the intestine could play a key role in aging.
"A URV-led study finds that two of these receptors are associated with age-related metabolic changes and could therefore help in the development of strategies for healthy ageing."
National Center to Reframe Aging teams up with California Department of Aging for Older Californians Month
"The National Center to Reframe Aging — the leading organization for proven communication strategies and tools to effectively frame aging issues — is working with the California Department of Aging (CDA) to help shift the tone of communication about aging in celebration of Older Californians Month (OCM) in May."
A groundbreaking discovery of a common master switch to cure Alzheimer’s, Parkinson’s, and other brain-related diseases
"A groundbreaking discovery of a common master switch to cure Alzheimer’s, Parkinson’s, and other brain-related diseases"
[TOO HIGH] Cannabis use disorder rapidly increasing among older adults
"Research shows that adults ages 65 and older are the fastest-growing age group to use cannabis in the United States. Use is particularly high among people living with HIV, an aging population that has reported taking this drug to manage HIV-related symptoms, side effects from antiretroviral therapy, pain, and moods."
[GET UP!] Sedentary behavior linked to cognitive decline
"Researchers have found that increased sedentary behavior -- time spent sitting or lying down -- in older adults was associated with worse cognition and brain shrinkage in areas related to risk for developing Alzheimer’s disease. For the study, researchers examined the relationship between sedentary behavior and neurodegeneration among 404 adults ages 50 and older. Study participants wore a watch that measured their activity continuously over the span of a week. Their sedentary time was then related to their cognitive performance and brain scans captured over a seven-year follow-up period. "
[CAFFEINATE ME] Coffee drinking tied to healthy aging in women
"Findings from a new study of almost 50,000 women followed for 30 years suggest that a morning cup of coffee might do more than boost energy; it could also help women stay sharp, strong and mentally well as they age. The analysis found that women who drank caffeinated coffee in midlife were more likely to exhibit healthy aging. However, the researchers didn’t find any links with tea or decaf coffee, and drinking more cola was tied to a significantly lower chance of healthy aging."
[TUNE IN] Timing exercise to your internal clock may boost healthy aging
"Timing and consistency of an individual's daily activity may be associated with improved cardiorespiratory fitness and walking efficiency — two key indicators of healthy aging, researchers say. They found that older adults with earlier and more consistent daily activity patterns had better heart and lung fitness compared with those with later or more irregular schedules."
[GET ENGAGED!] Engaging in social activities could prolong your life
"Social engagement may help older individuals live longer, according to a recent study. Researchers analyzed data from 2,268 US individuals ages 60 years and older who completed the Psychosocial and Lifestyle Questionnaires and provided blood samples in 2016. They found a strong association between engaging in social activities and a low risk of four-year mortality. Overall, high social engagement was associated with a 42% lower mortality risk than low engagement."
Study reveals how social networks shape health in later life
"A new study sheds light on the powerful connection between social networks and health in later life and reveals a surprising path for improving health equity among older adults."
New health assessment tool gauges body’s biological age
"The tool uses medical history and routine lab results to gauge body and organ age and to predict risk of disability and death."
During aging, do people with Down syndrome face a higher risk of cardiovascular disease than other individuals?
"Because life expectancy for individuals with Down syndrome has increased dramatically, investigators assessed the risk of age-related cardiovascular diseases in this population. As reported in the Journal of Internal Medicine, the researchers found increased risks of various cardiovascular diseases compared with the general population. "
Mount Sinai researchers in semifinals of $101 million XPRIZE Healthspan, a competition seeking innovative approaches to aging well
"Novel Mount Sinai trial targets key drivers of immune and tissue aging, offering hope to restore vitality and health in older adults"
Low-dose rapamycin improves muscle mass and well-being in aging adults
"Low-dose, intermittent rapamycin administration over 48 weeks is relatively safe in healthy, normative-aging adults, and was associated with significant improvements in lean tissue mass and pain in women"
Exercise helps improve how our brain ages
"Yes, exercise makes a positive difference for brain health"
Is your heart aging too fast?
"MRI technology reveals unhealthy lifestyles add decades"
Black tea and berries could contribute to healthier aging
"Higher intakes of black tea, berries, citrus fruits and apples could help to promote healthy ageing, new research has found."
Does your biological age affect your risk of dementia?
"People whose biological age is higher than their chronological age may be more likely to develop dementia than people whose biological age matches or is lower than their chronological age, according to a study published on April 30, 2025, online in Neurology®, the medical journal of the American Academy of Neurology. Biological age is based on biomarkers of aging such as lung function, blood pressure and cholesterol."
Substance use accelerates brain aging through distinct molecular pathways, groundbreaking study reveals
"Researchers identify unique biological mechanisms that cause premature aging in the brains of individuals with alcohol, opioid, and stimulant use disorders"
Study: middle-aged Americans are lonelier than adults in other countries, age groups
"In the USA it is more common for the middle aged to be lonely than those in older groups – a result only shared with the Netherlands."
Severe, lasting impairment that some consider ‘worse than death’ affects many residents after long-term care admission
"20% of residents newly admitted to long-term care became permanently unable to make everyday decisions for themselves within five years, according to new research from Bruyère Health Research Institute and ICES. "
Social isolation linked to poor diet in older women
"A new UBC study finds that persistently isolated older Canadian women are more likely to fall short of recommended fruit and vegetable intake, leading to poorer overall diet quality."
Reveals the spatiotemporal distribution patterns and future risks of five major cancers worldwide
"Recently, a study published in the Journal of Geo-Information Science has highlighted a significant upward trend in the mortality rates of major cancers worldwide. Conducted by Associate Professor Shen Li and his team at the School of Remote Sensing and Information Engineering, Wuhan University, the research analyzed data from the Global Burden of Disease (GBD) study and the World Bank, covering the mortality rates of lung, colorectal, stomach, liver, and pancreatic cancers in 200 countries between 2011 and 2019. The team employed a Multiscale Geographically Weighted Regression (MGWR) model to extract spatial heterogeneity between cancer mortality rates and various influencing factors—such as the proportion of the population aged 65 and above, smoking, alcohol consumption, unhealthy diets, and economic indicators—and used an ARIMA model to quantitatively analyze the temporal trends and cyclical fluctuations of these cancers."
Researchers identify a key biological mechanism that promotes healthy aging
"A study published in Aging Cell has identified immune resilience as a key driver of salutogenesis—the active process of promoting health and well-being."
Science confirms what an only child already knows: caregiving alone is tough
"University of Missouri researchers explore how caring for a parent differs when you’re among siblings compared to being an only child"
People’s functional status improved in all labour market groups during the first year of the COVID-19 pandemic
"There were no major changes in the functional status of older working-aged Europeans in 2004–2022, a recent study finds. Among both women and men, the unemployed have more functional limitations than the employed. Surprisingly, the likelihood of functional limitations decreased in all labour market groups during the first year of the COVID-19 pandemic, and this was most evident in countries where COVID-19 related restrictions were moderate."
DNA methylation entropy: A new way to track and predict aging
"We find that epigenetic clocks based on the entropy of methylation states predict chronological age with similar accuracy as common approaches that are based on methylation levels of individual cytosines."
National Center to Reframe Aging teams up with West End Home Foundation
"The National Center to Reframe Aging — the leading organization for proven communication strategies and tools to effectively frame aging issues — is partnering with The West End Home Foundation (WEHF), an independent charitable foundation located in Nashville, Tennessee."
JMIR Aging launches new section focused on advance care planning for older adults
" JMIR Aging, a leading open access journal focused on digital health and aging, announced the launch of a new dedicated section on “Advance Care Planning for Older Adults.” This timely addition will provide a crucial platform for cutting-edge research examining how digital health tools can empower older adults in making informed decisions about their future health care needs and actively involve their caregivers in this vital process."
Natural supplement may decrease biological aging and improve muscle strength
"Our findings suggest that the Cel System supplement range may effectively reduce biological age and improve health metrics, warranting further investigation into its mechanistic pathways and long-term efficacy"
Aging reimagined: UT Health San Antonio study shifts focus from inevitable decline to optimizing resilience
"Robust immune systems may offer up to 15.5-year survival advantage"
CIAO Study: A long and ongoing look at the secrets of human longevity and healthy aging
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